Occult Hepatitis B Virus infection in a cohort of patients with chronic Hepatitis C

MI Naga, MA Amin*, DA Algendy, AI El Badry, MM Fawzi, AR Foda, SM Esmat, SM Gabal, D Sabry, M Kamal, LA Rashed

Introduction: The prevalence of occult hepatitis B, defi ned by absence of HBsAg and HBV DNA, ranges widely in patients with hepatitis C. This may infl uence the treatment of hepatitis C and the severity of liver disease

Aim of work and methods: Was to determine the prevalence of occult hepatitis B virus infection and liver of HBsAg negative patients with chronic hepatitis C and to evaluate its clinical consequences on liver pathology and its impact on the response to treatment with peg-IFNa and Ribavirin. Immunohistochemistry staining for hepatitis B surface antigen and HBV DNA detection was assessed retrospectively on liver biopsies of HCV positive/ HBsAg negative patients before treatment.

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Published on: Jul 26, 2019 Pages: 17-21

Full Text PDF Full Text HTML DOI: 10.17352/ahr.000022
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