Dr.
Qiu, Sheng-Xiang is a Professor and the Director of the Natural Product
Chemical Biology & Drug Discovery Program of South China Botanical Garden
of Chinese Academy of Sciences. He completed his undergraduate and M. S.
degrees in China and received his PhD from University of Illinois at Chicago in
the United States. Dr. Qiu led a research team to discover bioactive natural
products from plants for the treatment of infectious diseases, immune
disorders, cancer, diabetes, and hyperuricemia. His team applies advanced
molecular and cell biology technologies, computational chemistry, and network
pharmacology to decipher the mechanism of action of the active compounds from
plants to tackle key issues in natural product-based drug discovery. After
decades of hard work, Qiu’s team has made several groundbreaking achievements.
They discovered that several xanthones in mangosteem and phloroglucinols in
myrtle are novel antimicrobial agents against methicillin-resistant bacteria.
They identified plant Pinosylvin monomethyl ether possessed strong antifungal
activity against pathogenic fungi associated with aflatoxin B1 accumulation,
likely a cause of the high incidence of liver cancer in China. They discovered
Rhodomyrtone as the first plant-derived broad-spectrum antiviral chemical
against SARS-CoV-2 by modulating host defense. They identified a stilbenoid as
the first anti-HPV natural small molecule with dual function of blocking HPV infection
and reversing HPV-induced cancerous transformation of cervical cells.
Cajaninstilbene acid from pigeon pea was identified to be the first
plant-derived AhR agonist with the potential to treat psoriasis. Dr. Qiu has
published >200 papers in peer-reviewed journals and holds >30 patents.
Research
Interest: Natural
product medicinal Chemistry/chemical biology; Pharmacology; signaling
transduction; Drug discovery.
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."